Ruijter, E.; Orru, R.; Znabet, A.; Polak, M.; Turner, N. (VER CHRISTELIJK WETENSCHAPPELIKJK ONDERW) “Stereoselective preparation of prolyl peptide compounds used e.g. for catalysis of organochemical reactions and as a viral inhibitor involves reacting 1-pyrroline compound with carboxylic acid compound and nitrile compound”. Patent Number: WO2011103932-A1.
Ruijter, E.; Orru, R.; Znabet, A.; Polak, M.; Turner, N. (VER CHRISTELIJK WETENSCHAPPELIKJK ONDERW) “Forming alpha-acyloxy beta-formamido amide compounds to form (S)-pyrrolidine-2-carboxylic acid amide compounds e.g. telaprevir and boceprevir compounds involves reacting N-(2-oxo-ethyl)-formamide compound with alcohol and cyanide compound”. Patent Number: WO2011103933-A1.