Kruithof, A; Mulder, J.R.; Ruiz, J.M.; Janssen, E.; Mooijman, M.; Ruijter, E.; Fonseca Guera, C.; Bickelhaupt, F.M.; Orru, R.V.A. “Integrative Theory/Experiment-Driven Exploration of a Multicomponent Reaction towards Imidazoline-2-(thi)ones” Eur. J. Org. Chem. 2017, 1, 104-112.

arteurjoc2017

Mampuys, P.; Neumann, H.; Sergeyev, S.; Orru, R.V.A.; Jiao, H.; Spannenberg, A.; Maes, B.U.W.; Beller, M. “Combining Isocyanides with Carbon Dioxide in Palladium-Catalyzed Heterocycle Synthesis: N3-Substituted Quinazoline-2,4(1H,3H)-diones via a Three-Component Reaction” ACS Catal. 2017, 7, 5549-5556.

mampuysacscatal

Collet, J.W.; Foley, C.; Shaw, A.Y.; Orru, R.V.A.; Ruijter, E.; Hulme, C. “Copper (I) Catalyzed Oxidative Hydrolysis of Ugi 3-Component and Ugi-Azide Reaction Products towards 2o α-Ketoamides and α- KetotetrazolesOrg. Biomol. Chem. 2017, 15, 6132-6135.

jurrien

van der Born, D.; Pees, A.; Poot, A.J.; Orru, R.V.A.; Windhorst, A.D.; Vugts, D.J. “Fluorine-18 Labelled Building Blocks for PET Tracer Synthesis” ChemSocRev 2017, 46, 4709-4773.

dionchemsocrev2017

Kruithof, A; Vande Velde, C.M.L.; Ruijter, E.; Orru, R.V.A. “Thiazine-2-thiones as Masked 1-Azadienes in Cascade Dimerization Reactions” Molecules 2017, 22, 541.

Thomas, B.; Rombouts, J.A.; Gupta, K.B.S.S.; Orru, R.V.A.; Lammertsma, K.; de Groot, H.J.M. “Determination of Controlled Self-Assembly of a Paracrystalline Material by Homology Modelling with Hybrid NMR and TEMChem. Eur. J. 2017, 23, 9346-9351.

chem201701172-toc-0001-m

Thomas, B.; Rombouts, J.A.; Oostergetel, G.T.; Gupta, K.B.S.S.; Buda, F.; Lammertsma, K.; Orru, R.V.A.; de Groot, H.J.M. “A Hybrid Solid State NMR and Electron Microscopy Structure Determination Protocol for Engineering Advanced Para-crystalline Optical Materials” Chem. Eur. J. 2017, 23, 3280-3284.

rombouts2017

Cioc, R.C.; Schaepkens van Riempst, L.; Schuckman, P.; Ruijter, E.; Orru, R.V.A. “Ugi Four-Center Three-Component Reaction as a Direct Approach to Racetams” Synthesis 2017, 49, 1664-1674.

Cioc, R.C.; Estévez, V.; van der Niet, D.J.; Vande Velde, C.M.L.; Turrini, N.T.; Hall, M.; Faber, K.; Ruijter, E.; Orru, R.V.A.  “Stereoselective Synthesis of Functionalized Bicyclic Scaffolds by Passerini 3-Center-2-Component Reactions of Cyclic Ketoacids“, Eur. J. Org. Chem. 2017, 9, 1262-1271.

cioc-eurchemj

Turrini, N.G.; Cioc, R.C.; van der Niet, D.J.H.; Ruijter, E.; Orru, R.V.A.; Hall, M.; Faber, K. “Biocatalytic access to nonracemic γ-oxo esters via stereoselective reduction using ene-reductases”, Green Chem. 2017, 19, 511-518.

razvan-green-chem2

Estévez, V.; Kloeters, L.; Kwietniewska, N.; Vicente-García, E.; Ruijter, E.; Orru, R.V.A. “Ugi-Type Reactions of Spirocyclic Indolenines as a Platform for Compound Library Generation”, Synlett 2017, 28, 376-380.